Manchester Utd vs Chelsea Prediction & Betting Tips (20 September)

For this meeting, Manchester United is still deprived of the titular defender Lisandro Martinez. He was joined by the infirmary by the attacker recruited at great costs this summer Matheus Cunha. Mason Mount and defender Diogo Dalot are uncertain. Captain Bruno Fernandes (1 PL goal) is one of the only Red Devils to hold his rank for some time. Note all the same that the Mbeumo winger (1 PL goal) makes promising beginnings under his new tunic. The other offensive recruit SESKO started on the bench in the first three championship games. Behind, the young French defender Yoro is becoming more and more important while the Turkish goalkeeper Bayindir is struggling to convince. During the offseason, Manchester United did not retain the porter Onana (Trabzonspor), the defender Lindelöf (Aston Villa), the Middle Eriksen (without club) and the offensive Garnacho (Chelsea), Antony (Betis), Hojlund (Napoli), Rashford (Barcelona) and Sancho (Aston Villa). Conversely, the porter Lammens (Antwerp), the young side Diego Leon (Cerro Porteno) and the attackers Matheus Cunha (Wolverhampton), Mbeumo (Brentford) and Sesko (Leipzig) were recruited. For this meeting, Chelsea could find the offensive taulier Palmer.

It is announced uncertain as is the ESSUGO midfielder and the recent recruit Garnacho. Take place the Badiashile defender, the Lavia midfielder and the striker Delap. Finally, the winger Mudryk is always suspended for doping. The Brazilian Joao Pedro (2 goals and 2 PL passes) is already preponderant for the blues. The wingers Estevao (1 PL pass) and Pedro Neto (1 PL goal) are well available as are the Fernandez framework (2 goals and 1 PL) and Caicedo. This summer, Chelsea was still very active on the transfer market. We can notably mention the departures of attackers Jackson (Bayern Munich), Madueke (Arsenal) and Nkunku (AC Milan). In the opposite direction, arrived at the club the lateral Hato (Ajax), the Essugo (Sporting) and Buonanotte (Brighton) circles as well as the offensive Joao Pedro (Brighton), Gittens (Dortmund), Garnacho (Manchester United), Delap (Ipswich) and Estevao (Palmeiras). 

In terms of team news, United remain without several key figures—Matheus Cunha, Mason Mount, Diogo Dalot, and Lisandro Martinez are all sidelined. Amorim is expected to stick with Altay Bayindir in goal, flanked by a back three of Yoro, De Ligt, and Shaw. Patrick Dorgu and Amad Diallo will provide width, while Kobbie Mainoo could earn his first league start of the season alongside Casemiro in midfield. Chelsea, too, have their share of absentees, with Liam Delap, Levi Colwill, and Dario Essugo ruled out. Palmer remains a doubt, but Estevao and Garnacho offer dynamic options out wide, and Reece James is likely to return at right-back.

Despite Chelsea’s statistical edge and recent form, Old Trafford has a way of bending narratives. United’s tactical tweaks and home resilience could tilt the balance in their favor. Expect a tightly contested affair, with United exploiting transitional moments and Chelsea probing through possession. A 2-1 scoreline in favor of Manchester United feels plausible—Sesko to announce himself with a debut goal, Fernandes to convert from the spot, and Chelsea to respond late through Joao Pedro. It won’t be a stroll, but it could be a statement.

• Summary: Manchester United is going head to head with Chelsea starting on 20 Sept 2025 at 16:30 UTC at Old Trafford stadium, Manchester city, England. The match is a part of the Premier League .