Cagliari vs Inter Prediction & Betting Tips (27 September)

Cagliari welcome Inter Milan to the Unipol Domus on September 27 with renewed optimism after a gritty 2-1 win over Lecce, powered by a brace from Andrea Belotti. Under the guidance of Fabio Pisacane , the Sardinians have stitched together a promising run—two consecutive victories and a steady goal-per-game average. Pisacane’s tactical tweaks have brought balance to a side that previously struggled to convert possession into points. Sitting fifth in the table with seven points, Cagliari now face a stern test against a historically dominant opponent, but the mood in the camp is anything but timid.

Inter Milan, meanwhile, arrive in Sardinia fresh off a morale-boosting 2-0 win over Ajax, where Marcus Thuram’s double underscored their attacking depth. Coach Cristian Chivu, stepping in for Simone Inzaghi who is focused on Champions League duties, has kept the Nerazzurri competitive despite recent inconsistencies. Inter’s domestic form has been patchy—three wins and three losses in their last six—but their scoring prowess remains intact, averaging over two goals per match. Defensive lapses, however, have crept in, with nine goals conceded across those fixtures, a vulnerability Cagliari will look to exploit.



Historically, Inter have dominated this fixture, winning 11 of their last 15 Serie A meetings and scoring in 37 consecutive home games. Yet, Cagliari’s recent resurgence and home advantage could tilt the narrative. Belotti’s form, coupled with Pisacane’s compact midfield setup, may frustrate Inter’s rhythm. The Nerazzurri’s tendency to concede early—four first-half defeats in their last six—adds intrigue to a matchup that could defy expectations. With Lautaro Martinez likely to be rested ahead of European commitments, Inter may lean on Thuram and Frattesi to carry the attacking load.

In a clash of ambition versus pedigree, the prediction leans toward a surprise: Cagliari 2, Inter 1. The hosts, buoyed by form and fervor, could snatch an early lead and hold firm against a side juggling multiple competitions. Inter’s firepower ensures they won’t go quietly, but Cagliari’s momentum and tactical discipline might just be enough to seal a statement win. Expect a tense, tactical battle with moments of brilliance—and a scoreline that reflects a shift in Serie A’s undercurrent.

• Summary: Cagliari is going head to head with Inter starting on 27 Sept 2025 at 18:45 UTC at Unipol Domus stadium, Cagliari city, Italy. The match is a part of the Serie A .