Sassuolo vs Juventus Prediction & Betting Tips (13 September)

Sassuolo host Juventus on Sunday, 13 September 2026 at the Mapei Stadium in Reggio Emilia, in one of the standout fixtures of Serie A matchday 4. Juventus arrive unbeaten under Luciano Spalletti with seven points from three games, while Sassuolo have collected four points from their opening three matches of the 2026/27 campaign. The European odds ahead of kick-off firmly favour the visitors, with Juventus priced at 1.68 to win, the draw at 4.02, and a Sassuolo home victory at 6.00.

Sassuolo's 2026/27 squad, built around Arijanet Muric in goal and the experienced Nemanja Matic in midfield, showed flashes of quality early in the season. The Neroverdi fought to an entertaining 2-2 draw away at Bologna last weekend after earlier beating Torino 2-1 at home, though they were beaten 2-1 by Atalanta on the opening day. Coach Fabio Grosso is without several key men, with Sebastian Walukiewicz, Fali Candé, Edoardo Pieragnolo, Daniel Boloca and Ismaël Koné all unavailable.

Juventus, meanwhile, have made a quietly efficient start to the season. The Bianconeri edged Frosinone 1-0 away on the opening day, beat Parma 2-0 at the Allianz Stadium, and then snatched a dramatic 1-1 draw against AC Milan thanks to Federico Gatti's stoppage-time header. Spalletti's new-look squad featuring Guglielmo Vicario, Gleison Bremer, Lloyd Kelly, Jonathan David, Jérémie Boga and Randal Kolo Muani was far more convincing in the 2-0 win over Parma, although injuries to Kenan Yildiz, Khéphren Thuram, Weston McKennie and Edon Zhegrova remain a concern.

Recent history strongly favours Juventus: the reverse fixture in January 2026 ended Sassuolo 0-3 Juventus, and the sides also drew 1-1 in Turin last March. Sassuolo's depleted defence has already shown vulnerability against organised attacks, and with the visitors conceding just one goal in their first three league games, the away win at 1.68 looks generously priced. Our prediction: Sassuolo 0 : 3 Juven