St. Louis City 2 vs Los Angeles FC II Prediction & Betting Tips (28 September)

St. Louis City SC II welcomes Los Angeles FC II to Energizer Park on September 28 in a clash that pits one of MLS Next Pro’s most consistent performers against a side still searching for rhythm. The hosts, currently sitting third in the standings, have built their campaign on a foundation of attacking flair and defensive resilience. With eight wins in their last twelve matches, they’ve shown a knack for controlling tempo and punishing lapses. Head coach Bobby Murphy has leaned into a high-pressing system that suits the likes of Wan Kuzain and John Klein, both instrumental in midfield transitions and chance creation.

Los Angeles FC II, meanwhile, arrives in St. Louis with a mixed bag of form and a recent 3-1 defeat to Real Monarchs still fresh. Marius Aiyenero’s late goal in that match was a bright spot, showcasing his ability to find space and finish under pressure. However, inconsistency has plagued the squad, with seven losses in their last twelve outings. Head coach Enrique Duran has struggled to find a settled lineup, often rotating between youth prospects and experienced reserves. Their away record remains a concern, with just a 25% win rate on the road and an average of over two goals conceded per match.

Historically, this fixture has tilted in favor of St. Louis City II, who have won three of the last four meetings, including a 2-1 victory in October 2024 that mirrors our predicted scoreline. These encounters have been goal-heavy, with both teams scoring in every match and a combined average of over three goals per game. St. Louis’s home advantage and superior xG metrics—1.76 at home compared to LAFC II’s 1.25 away—suggest they’ll dictate proceedings again. Expect Klein and Kuzain to orchestrate the midfield while the backline, led by Josh Maher, aims to contain Aiyenero’s threat.

With momentum, form, and tactical clarity on their side, St. Louis City II is poised to edge this contest 2-1. LAFC II will likely find the net, perhaps through a moment of individual brilliance, but their defensive frailties and lack of cohesion could prove costly. The match promises intensity and attacking intent, but the hosts’ structured approach and clinical edge should see them through. For fans and analysts alike, this is a fixture that blends youth development with competitive fire—MLS Next Pro at its most compelling.